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Oct 28, 2016

The Many Biological Actions of Resveratrol

Biological Action                               Reference

Anti-histamine action (allergy)                           Planta Medica 2004 Apr; 70 (4):305-309

Anti-inflammatory agent J Chemotherapy          2004 Nov; 16 Suppl 4:3-6
                                                                     J Environ Pathology Toxicology Oncology 2004; 23 (3):215-226

COX-2 inhibitor (anti-inflammatory)                  Inflammation Research 2005 Apr; 54 (4):158-162            
Potentially helpful for Rheumatoid arthritis        International Immunopharmacology 2005 May; 5 (5):849-856

Inhibits pancreatitis                                        World J Gastroenterology 2005; 11:3171-3174

ACE Inhibitor properties                                 European J Pharmacology 2005 May 16; 515 (1-3):1-9

Prevents blood clots                                       Blood Coagulation Fibrinolysis 2004 Sept; 15 (6):441-446

Reduces LDL cholesterol                               Life Sciences 2003 Aug 1:73 (11):1393-1400

Reduces triglycerides                                    Life Sciences 2003 Aug 1:73 (11):1393-1400

Raises HDL "good" cholesterol                      J Agric Food Chemistry 2005 May 4; 53 (9): 3403-3407
           
Inhibits arterial plaque without altering 
cholesterol                                                   Int J Mol Med 2005 Oct; 16 (4):533-540

Preserves or stimulates                                J Agric Food Chem 2005 May 18; 53 (10):4182-4186   
   superoxide dismutase (antioxidant)            Free Radical Biology Medicine 2003 Apr 1; 34 (7):810-817

Elevates glutathione (antioxidant)                 J Agric Food Chem 2005 May 18; 53 (10):4182-4186
                                                                 Arch Biochem Biophy 2000 Sept 15; 381 (2):253-263

Elevates catalase activity                           Life Science 2003 May 2; 72 (24):2741-2750

Prolongs life of cells via Sirtuin 1 gene         Trends Pharmacological Sciences 2005; 26:94-103

Promotes DNA repair (via Sirtuin 1 gene)      Nature 2003 Sep 11; 425 (6954):191-196

Inhibits abnormal new blood vessel formation    J Physiology Pharmacology 2005 Mar; 56 Suppl 1:51-69
  (angiogenesis)

Inhibits dietary sugar absorption                      Journal Natural Products 2001; 64:381-384        
Regulates blood sugar                                   J Agric Food Chemistry 2005 May 4; 53 (9): 3403-3407

Normalizes blood pressure                             J Hypertension 2000 Dec; 18 (12):1833-1840

Calms effects of estrogen (estrogen blocker)   J Steriod Biochemical Mol Biology 2005 Apr; 94 (5):431-443

Prevents bone loss                                       J Medicinal Food 2005 Spring; 8 (1):14-19            

Protects retinal cells
 (retinal pigment epithelium)                          Chemical Biological Interaction 2005 Jan 15; 151 (2):143-149
  
Increases sperm count                                J Nutrition 2005 Apr; 135 (4):757-760

Inhibits viral growth (influenza)                    J Infectious Disease 2005 May 15; 191 (10):1719-1729
                    
Inhibits viral growth (HIV)                           J Pharm Science 2004 Oct; 93 (10):2448-2457

                                                     

Inhibits viral growth (herpes)                      Antiviral Research 2004 Jan; 61 (1):19-26; 1999
   Oct; 43 (3):145-155

Antibiotic against bacteria (Chlamydia)      Atherosclerosis 2003 Dec; 171 (2):379-380

Antibiotic against bacteria (H. pylori)         Am J Gastroenterology 2003 Jun; 98 (6):1440-1441

Inhibits growth of fungi (yeast, mold)        J Agriculture Food Chemistry 2003 Feb 26; 51(5):1464-1468 
  
Inhibits initiation of tumors                      Proc Nati Sci Council Repub 
                                                             China B 1999 Jul; 23 (3):99-106
                                                                                                   
Eradicates plaque in brain
 (beta amyloid toxicity)                           British J Pharmacology 2004 Mar; 141 (6):997-1005

Chelates metals (copper)                       Biochem Pharmacology 1997 May 9; 53 (9):1347-1355
                 
Anti-leukemia agent                               Leukemia Lymphoma 2002 May; 43 (5):983-987

Inhibits prostate cancer                         Cancer Epidemiology Biomarkers Prevention 2005
   Mar; 14 (3):596-604

Inhibits breast cancer                           Molecular Nutrition Food Research 2005 May; 49 (5):462-471
  
Inhibits melanoma                               Neoplasia 2005 Jan; 7 (1):37-47

Inhibits ovarian and cervical cancer      Anticancer Res 2004 Sep-Oct; 24 (5A):2783-2840

Inhibits lymphoma                             Cancer Letters 2001 Feb 10; 163 (1):43-49

Exhibits Viagra-like effects 
(nitric oxide)                                      Free Radical Biology Med 2004 Mar 15; 36 (6):774-781
  
Novel molecule for organ transplants   World J Gastroenterology 2005 Aug 14; 11(30):4745-4749  
  
Non-toxic                                          J Nutrition 2002 Feb; 132 (2):257-260

Inhibits growth of tumors                   Drug Experimental Clinical Research 1999; 25 (2-3):65-77
                                                                                                    
Inhibits spread of tumors                   Proc Nati Sci Council Repub China B 1999 Jul; 23 (3):99-106
  
Targets multiple genes 
(silencing/activation)                        J Nutritional Biochemistry 2005 Aug; 16 (8):449-466

Protects brain cells                         Ann N Y Academy Sciences 2003 May; 993:276-286

Inhibits hepatitis
 (liver inflammation)                       Hepatogastroenterology 2002 Jul-Aug; 49 (46):1102-1108
  
Inhibits liver cancer                       World J Gastroenterology 2003 Oct; 9 (10):2341- 2343
 
Inhibits brain cancer                     Molecular Cancer Therapy 2005 Apr; 4 (4):554-561

Inhibits pancreatic cancer             Pancreas 2002 Nov; 25 (4):e71-76

Inhibits kidney cancer                  Cancer Biology Therapy 2004 Sept; 3 (9):882-888

Inhibits colon cancer                    International Cancer 2005 June 10; 115 (2):194-201

NO CLAIM CAN BE MADE THAT RESVERATROL DIETARY SUPPLEMENTS
HAVE THE SAME ACTION AS DEMONSTRATED IN THE ABOVE EXPERIMENTS