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May 18, 2010

Antidepressants shown to be ineffective

According to JAMA studies are showing that antidepressants such as tricyclics and selective serotonin reuptake inhibitors (SSRIs: Zoloft, Paxil, Prozac) and the targeted norepinephrine drugs (Effexor, Paxil) are no more effective than a placebo. A JAMA study in January 2010 did an analysis of six large experiments in which depressed patients received either a placebo or an antidepressant and the drugs effect was nonexistent to negligible compare to the placebo in patients with mild, moderate and even severe depression.