A recent study, examined the effects of two diabetic drugs rosiglitazone and pioglitazone, both in a category of diabetic drugs called thiazolidinedions, and their effect on cardiovascular illnesses such as acute myocardial infarctions, stroke, heart failure, and death. Interestingly, when the two prescriptions were compared to each other, rosiglitazone was associated with a higher increased risk of stroke, heart failure, and all-cause mortality than pioglitazone. According to these studies, as a general rule pioglitazone has the same actions on blood sugar, but appears to be safer than the other option in this category. While safer, all thiazolidinediones are associated with higher heart failure risks compared to other diabetic medications and placebo.
Dr. Kerry Ferguson
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