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Aug 6, 2014

Probiotic Treatment of Sensitive Skin

A recent experiment involving a randomized double blind placebo-controlled trial sheds light on the ‘gut-skin connection’.  In the experiment, half of the participants were provided with a sachet containing powder of Lactobacillus paracasei.  The other group was provided with a placebo sachet containing the food additive maltodextrin.  The study duration was 2 months.

The study included 64 Caucasian women aged 18 to 40 years selected for sensitive skin based  a questionnaire, whether or not they had a positive reaction to capsaicin.  The effects of Lactobacillus paracasei on skin sensitivity and skin barrier function recovery were the primary outcome measures.
The results of the experiment showed Lactobacillus paracasei to have a positive effect on skin sensitivity, skin barrier function recovery, and key associated physiological parameters. It also showed, there was statistically significant improvement in perceived skin roughness in the intervention group vs placebo.

In his analysis, Traub stated how the double-blind experiment reinforces the concept of an inside-out, outside-in approach to the treatment of common skin disorders such as atopic dermatitis, psoriasis, and acne. ‘In order to provide comprehensive care to patients with sensitive skin, probiotic strains should be selected with proven benefit for these conditions and ideally prescribed at proven-effective dosages. We are at the cusp of a much more sophisticated understanding of the therapeutic applications of probiotics not only for skin disease but for a great number of immune-mediated conditions that are intimately tied to the fact that the vast majority of our immune system is located in the gut,’ he concludes.